Company Description

"Beacon Bio is innovating regenerative tissue grafts using 3D printing and novel material science technology. Our IP portfolio includes an issued patent on circular/radial eardrum devices and a pending patent on a melt extrudable 3D printing ink for tissue grafts. The latter includes a method of synthesizing a biodegradable, elastomeric polymer material for use in the ink.

Our first device, PhonoGraft, is turning up the volume on the eardrum via a biodegradable material and biomimetic architecture. PhonoGraft represents a completely synthetic option that remodels over time into native tissue matching the original print path to generate better acoustic outcomes. Due to its synthetic nature and the precisely engineered elastomeric material, the grafts are also easy to place and manipulate, potentially negating the need for general anesthesia and enabling grafts to be placed through the ear canal in a clinic setting.

Importantly, the circular and radial architecture of the TM is crucial for enabling sound conduction across both low and high frequencies. Our acoustic data shows an even better response for our 3D-printed circular and radial TM grafts than native human TM tissue. Importantly, we believe that our technology can be used to augment the TM's native architecture to augment the TM's structure with additional radial stiffness and therefore enhance sound conduction in patients with hearing loss. As a secondary market, we plan to further develop our technology for a novel device called AudioGraft, for use in patients with hearing loss as an alternative to or supplement to conventional hearing aids."

Contact Person

Nicole Black
CEO and Co-Founder

Nicole Black, PhD is the CEO and Co-Founder of Beacon Bio, a company designing novel tissue grafts using 3D printing and materials science technologies. Their first product, PhonoGraft, is an innovative device for treating eardrum perforations with improved healing and hearing outcomes. For the past 6 years, Nicole has been working at the Wyss Institute for Biologically Inspired Engineering at Harvard and at Mass Eye and Ear hospital. Nicole holds a BS in Biomedical Engineering from Boston University and an SM and PhD in Engineering Sciences from the Harvard John A. Paulson School of Engineering and Applied Sciences with a minor in the Speech and Hearing Bioscience and Technology Program through the Harvard Division of Medical Sciences.